My research interests encompass the physics and mathematics of imaging with Magnetic Resonance. Presently my research is directed in part towards exploration of rapid MRI scanning methods using spiral and other non-Cartesian k-space trajectories for dynamic imaging of function. Using spiral techniques, we have developed MRI pulse sequences and processing methods for mapping cortical brain function by imaging the metabolic response to various stimuli, with applications in the basic neurosciences as well as for clinical applications. These methods develop differential image contrast from hemodynamically driven increases in oxygen content in the vascular bed of activated cortex, using pulse sequences sensitive to the paramagnetic behavior of deoxyhemoglobin or to the blood flow changes. Other applications include imaging of contrast uptake in the breast.
Greicius MD, Flores BH, Menon V, Glover GH, Solvason HB, Kenna H, Reiss AL, Schatzberg AF. Resting-State Functional Connectivity in Major Depression: Abnormally Increased Contributions from Subgenual Cingulate Cortex and Thalamus. Biol Psychiatry 62:2349-56 (2007).
Hu YL, Glover GH. 3D spiral technique for high resolution fMRI. MRM 58(5):947-51 (2007).
Gaab N; Gabrieli JDE; Glover GH; Resting in peace or noise: scanner background noise suppresses default-mode network. HBM 29:858-67 (2008).
Law CS; Liu C; Glover GH. Sliding Window SENSE Calibration for Reducing Noise in fMRI. Magn Reson Med. 2008 Nov;60(5):1090-103.
Chang CE; Cunningham JP; Glover GH. Influence of heart rate on the BOLD signal: The cardiac response function. NeuroImage 44:857-69 (2009).
Law CS; Glover GH. Interleaved Spiral-In/Out with Application to fMRI. Magn Res Med. 62:829-34 (2009).
Chang CE; Glover GH. Effects of model-based physiological noise correction on default mode network anti-correlations and correlations. NeuroImage 47:1448-59 (2009).
Chang CE; Glover GH. Time-frequency dynamics of resting-state brain connectivity measured with fMRI. NeuroImage 50:81-89 (2010).
Rakow-Penner R; Daniel B; Glover GH. Detecting Blood Oxygen Level Dependent Contrast in the Breast. JMRI 32:120-129 (2010).
Hamilton JP; Glover GH; Hsu JJ; Johnson RF; Gotlib IH. Modulation of Subgenual Anterior Cingulate Cortex Activity with Real-Time Neurofeedback. Hum. Brain Map. 32:22-31 (2011).
Chang CE; Glover GH. Variable Density Spiral-In/Out fMRI. Magn. Reson. Med. 65:1287-96(2011). PMID: 21500257.
Luo Q; Glover GH. Influence of Dense Array EEG Cap on fMRI Signal. Magn. Reson. Med 68:807-15 (2012).
Nguyen HM; Glover, GH. A Modified Generalized Series Approach: Application to Sparsely-Sampled fMRI. IEEE Trans Biomed Eng. 60:2867-77 (2013).
Chen JE, Jahanian H, Glover GH. Nuisance Regression of High-frequency FMRI Data: De-noising Can Be Noisy. Brain Connectivity 2017 May;38(5):2454-2465. doi: 10.1002/hbm.23532. Epub 2017 Feb 2. PMID: 28150892.
Islam H; Law CS; Weber K; Mackey S; Glover GH. Dynamic per slice Shimming for Simultaneous Brain and Spinal Cord fMRI. Mag Reson Med 81:825-38 (2019) PMID: 30284739 doi:10.1002/mrm.27388
Chen JE; Polimeni JR; Bollmann S; Glover GH. On the analysis of rapidly sampled fMRI data. Neuroimage 188:807-20 (2019).
Bio sketch with list of publications.
Last modified on April 10, 2019